About This Product

NAD⁺ (Nicotinamide Adenine Dinucleotide) NAD⁺ is a naturally occurring coenzyme present in all living cells and is a central component in numerous biochemical pathways. It plays a critical role in cellular metabolism, energy transfer, and redox balance. Due to its broad involvement in fundamental biological processes, NAD⁺ continues to be a subject of extensive scientific investigation across multiple research domains. Biochemical Function NAD⁺ exists in two interchangeable forms: the oxidized form (NAD⁺) and the reduced form (NADH). These forms participate in redox reactions that are essential for: • Electron transport in metabolic pathways such as glycolysis, the citric acid cycle, and oxidative phosphorylation • Mitochondrial activity and cellular energy balance in experimental models • Supporting the maintenance of cellular redox state under varying physiological conditions Research Applications and Focus Areas Studies involving NAD⁺ commonly investigate its role in: • Enzymatic activity: NAD⁺ serves as a co-substrate for enzyme families such as sirtuins and poly(ADP-ribose) polymerases (PARPs), which are implicated in DNA repair, epigenetic regulation, and cellular stress responses. • Metabolic regulation: Research explores how NAD⁺ levels correlate with cellular adaptation, mitochondrial efficiency, and overall bioenergetic status in various model systems. • Aging and stress response models: NAD⁺ is frequently studied for its involvement in pathways linked to longevity, cellular resilience, and age-associated molecular changes. Why NAD⁺ Is Widely Studied in Research Because NAD⁺ is integral to core cellular functions, it is widely used as a research tool for investigating metabolic regulation, oxidative stress, and cell signaling pathways. Its involvement in both nuclear and mitochondrial processes makes it a versatile molecule for exploring how cells respond to environmental, energetic, or genetic stressors in controlled scientific studies.